This content was paid for by the U.S. Department of Health and Human Services. Columbia Mom is proud to support the effort to share facts about COVID-19 vaccines. For more information or to find vaccines near you, visit vaccines.gov, text your ZIP code to 438829 (GETVAX), or call 1-800-232-0233.
Making decisions about your child’s health is one of the most important choices you’ll face. We recently partnered with the U.S. Department of Health and Human Services to share information about COVID, vaccinations, and how they relate to children so you can make the best-informed decision for your family.
And ultimately, it is YOUR CHOICE.
The guide below can help you find the locations in the Columbia area offering COVID vaccines for children ages 5+ and families. Talk to a doctor if you have questions about COVID vaccines.
Please Note: While we make every effort to crosscheck current links and details on our guides, we always encourage you to do the same before making final plans. If details are missing or incorrect, please let us know.
Downtown/Forest Acres/Rosewood
- Publix Super Markets, 501 Gervais St, Columbia, SC 29201: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- Publix Super Markets, 2800 Rosewood Dr, Columbia, SC 29205: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- CVS Pharmacy, 3312 Devine St, Columbia, SC 29205: Walk-ins and appointments available. It is highly recommended to make an appointment for pediatric (5–11 years old) COVID-19 vaccinations. The Pfizer vaccine is available.
- Walgreens, 4467 Devine St, Columbia, SC 29205: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Walgreens, 4467 Devine St, Columbia, SC 29205: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- CVS Pharmacy, 6090a Garners Ferry Rd, Columbia, SC 29209: Walk-ins and appointments available. It is highly recommended to make an appointment for pediatric (5–11 years old) COVID-19 vaccinations. The Pfizer vaccine is available.
- Walgreens, 4730 Forest Dr, Columbia, SC 29206: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Publix Super Markets, 4840 Forest Dr #10, Columbia, SC 29206: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- Vistara Pharmacy, 6323 N Main St, Columbia, SC 29203: Walk-ins accepted, call (803) 766-6075 to check on appointment availability.
- Walmart, 5420 Forest Dr, Columbia, SC 29206: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Sam’s Club, 5426 Forest Dr, Columbia, SC 29206: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Walmart, 7520 Garners Ferry Rd, Columbia, SC 29209: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
Cayce/West Columbia
- Walmart, 1355 Knox Abbott Dr, Cayce, SC 29033: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Walgreens, 1537 Charleston Hwy, West Columbia, SC 29033: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Walmart, 2401 Augusta Rd, West Columbia, SC 29169: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- CVS Pharmacy, 2410 Charleston Hwy, Cayce, SC 29033: Walk-ins and appointments available. It is highly recommended to make an appointment for pediatric (5–11 years old) COVID-19 vaccinations. The Pfizer vaccine is available.
- Nephron SC, INC, 4500 12th St Ext, West Columbia, SC 29172: Drive-up site with no waiting. Moderna and Pfizer first and second shots available.
- Walmart, 1019 Old Barnwell Rd, West Columbia, SC 29170: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
Irmo/Harbison
- Sam’s Club, 350 Harbison Blvd, Columbia, SC 29212: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Walmart, 360 Harbison Blvd, Columbia, SC 29212: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Publix Super Markets, 150 Harbison Blvd, Columbia, SC 29212: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- Kroger Pharmacy, 7467 St Andrews Rd #6, Irmo, SC 29063: No walk-ins accepted. Book an appointment online. The Pfizer and Moderna vaccines are available.
- Walmart, 1180 Dutch Fork Rd, Irmo, SC 29063: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Walgreens, 1251 Dutch Fork Rd, Irmo, SC 29063: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- CVS Pharmacy, 1330 Dutch Fork Rd, Ballentine, SC 29002: Walk-ins and appointments available. It is highly recommended to make an appointment for pediatric (5–11 years old) COVID-19 vaccinations. The Pfizer vaccine is available.
Chapin
- Walgreens, 1401 Chapin Rd, Chapin, SC 29036: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
Northeast/Blythewood
- Walgreens, 9001 Two Notch Rd, Columbia, SC 29223: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Walgreens, 2725 Clemson Rd, Columbia, SC 29229: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Walmart, 10060 Two Notch Rd, Columbia, SC 29223: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Publix Super Markets, 10128 Two Notch Rd, Columbia, SC 29223: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- Sam’s Club, 733 Fashion Dr, Columbia, SC 29229: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Walgreens, 4520 Hardscrabble Rd, Columbia, SC 29229: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Publix Super Markets, 4611 Hardscrabble Rd, Columbia, SC 29229: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- Walgreens, 175 Forum Dr, Columbia, SC 29229: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
Lexington
- Walgreens, 5220 Sunset Blvd, Lexington, SC 29072: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- Publix Super Markets, 100 Old Cherokee Rd, Lexington, SC 29072: Walk-ins and appointments available. Publix Pharmacy administers the Pfizer, Moderna, and Johnson & Johnson COVID-19 vaccines, including third doses and boosters, subject to eligibility. This includes the Pfizer COVID-19 vaccine for children ages 5–11.
- Walmart, 5556 Sunset Blvd, Lexington, SC 29072: Walk-ins and appointments available. The Pfizer and Moderna vaccines are available.
- Walgreens, 423 W Main St, Lexington, SC 29072: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
- My Pharmacy, 808 Hwy 378 Ste C, Lexington, SC 29072: Walk-ins and appointments available.
- Walgreens, 2418 Augusta Hwy Ste A, Lexington, SC 29072: Appointments are required to receive a COVID-19 vaccine. No walk-ins are accepted at this time. The Pfizer vaccine is available.
Don’t see one that best fits your needs? To find vaccines near you, visit vaccines.gov, text your ZIP code to 438829 (GETVAX), or call 1-800-232-0233.
